Category: Clinical Trials
Tight K e-bulletins
The Tight K trial is investigating maintenance of high-normal serum potassium for the prevention of dysrhythmias following coronary artery bypass graft surgery
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WOMAN-2 Trial
The WOMAN-2 trial investigates Tranexamic Acid (TXA) for the prevention of postpartum bleeding in women with anaemia
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Trauma Intact Results and News
Pharmacokinetic TRAUMAINTACT trial results show TXA is well tolerated & rapidly absorbed via IM route in bleeding trauma patients
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PREVENTT Trial Results and News
Preoperative IV iron is NOT superior to placebo to reduce need for blood transfusion when given to anaemia patients 10–42 days before elective major abdominal surgery
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HALT-IT Trial Results and News
HALT-IT trial found that TXA does NOT reduce deaths from stomach bleeding but increases the risk of thromboembolic events (deep vein thrombosis or pulmonary embolism)
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The CRASH-3 Results and News
Tranexamic Acid (TXA) is a safe, low cost, and widely available drug which could prevent deaths from TBI by as much as 20% depending on severity of the injury
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Clinical trial managers need recognition for their work
Expert trial managers with the training and experience to overcome operational challenges are often the difference between the success and failure of a clinical trial.
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WOMAN Trial Results and News
Can we prevent women from dying after childbirth? The WOMAN trial showed that if given within 3 hours, TXA can reduce the risk of death due to bleeding by one third.
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The CRASH-2 Results and News
Global trial CRASH-2 is now complete and shows new hopes to cut deaths from serious injury – a simple jab of Tranexamic Acid could save up to 100,000 lives a year.
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