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‘Her Life Matters’ Documentary is live
June 30, 2021 LSHTM CTU News CTU admin

This documentary ‘Her Life Matters’ asks why each year, world-wide tens of thousands of mothers bleed to death needlessly – lives that could be saved by a single injection of an inexpensive generic drug called tranexamic acid. Tranexamic acid was invented sixty years ago to stop mothers from bleeding to death after childbirth.   The Woman

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TXA Central
March 4, 2021 LSHTM CTU News CTU admin

TXA Central collates information about clinical trial research conducted on Tranexamic Acid and is a resource for health professionals caring for patients with acute severe bleeding.

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WOMAN-PharmacoTXA Trial
December 16, 2020 LSHTM CTU News CTU admin

The WOMAN-PharmacoTXA
trial investigates the intramuscular and oral solutions of TXA in women undergoing Caesarean Section with at least one known risk factor for PPH

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A CRASH-3 Trial Sub-Study Provides Evidence of TXA Benefit in TBI
December 14, 2020 LSHTM CTU News CTU admin

Effect of tranexamic acid on intracranial haemorrhage and infarction in patients with traumatic brain injury: a randomised trial

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Art for Maternal Health Awareness
December 7, 2020 LSHTM CTU News CTU admin

Sculpture artist, Moira Purver was commissioned by the WOMAN trial to create this spectacular bronze statue that depicts a mother on her knees holding her new baby in her arms just after giving birth.

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World Day of Remembrance for Road Traffic Victims: early txa treatment could save lives of road traffic victims, it's time to act
World Day of Remembrance for Road Traffic Victims
November 10, 2020 Emergency Care,LSHTM CTU News,Tranexamic Acid (TXA) CTU admin

The researchers call urgent TXA treatment of all trauma victims, ideally at the scene of the crash, could prevent over 100,000 premature deaths each year worldwide.

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Tight K trial is a new study investigating how potassium should be controlled following Coronary Artery Bypass Graft (#CABG) surgery
Tight K Trial is Recruiting!
October 26, 2020 Cardiovascular,LSHTM CTU News CTU admin

TRIAL UPDATE (10/20): CONGRATULATIONS to the NHS Barts Health research team for recruiting their first patients into the TIGHTK Trial!

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Trauma Intact Trial finds TXA can be given by a simple injection at the scene of injury
Trauma Intact Results and News
October 1, 2020 Clinical Trials,LSHTM CTU News,Tranexamic Acid (TXA),Trauma Care CTU admin

Pharmacokinetic TRAUMAINTACT trial results show TXA is well tolerated & rapidly absorbed via IM route in bleeding trauma patients

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The PREVENTT trial investigated preoperative intravenous iron to treat anaemia before major abdominal surgery
PREVENTT Trial Results and News
September 4, 2020 Clinical Trials,LSHTM CTU News CTU admin

Preoperative IV iron is NOT superior to placebo to reduce need for blood transfusion when given to anaemia patients 10–42 days before elective major abdominal surgery

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HALT-IT Trial results show TXA should not be used for GI bleeding patients
HALT-IT Trial Results and News
June 20, 2020 Clinical Trials,Emergency Care,LSHTM CTU News,Tranexamic Acid (TXA) CTU admin

HALT-IT trial found that TXA does NOT reduce deaths from stomach bleeding but increases the risk of thromboembolic events (deep vein thrombosis or pulmonary embolism)

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