Publications

151 entries « 1 of 4 »

2020

Picetti, Roberto; Miller, Lori; Shakur-Still, Haleema; Pepple, Tracey; Beaumont, Danielle; Balogun, Eni; Asonganyi, Etienne; Chaudhri, Rizwana; El-Sheikh, Mohamed; Vwalika, Bellington; Arulkumaran, Sabaratnam; Roberts, Ian; trial collaborators, WOMAN

The WOMAN trial: clinical and contextual factors surrounding the deaths of 483 women following post-partum haemorrhage in developing countries. Journal Article

BMC Pregnancy and Childbirth, 20 (1), pp. 409, 2020.

Abstract | Links | BibTeX

Ageron, Francois-Xavier; Gayet-Ageron, Angele; Ker, Katharine; Coats, Timothy J; Shakur-Still, Haleema; Roberts, Ian; Collaboration, Antifibrinolytics Trials

Effect of tranexamic acid by baseline risk of death in acute bleeding patients: a meta-analysis of individual patient-level data from 28 333 patients. Journal Article

BRITISH JOURNAL OF ANAESTHESIA, 124 (6), pp. 676–683, 2020.

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Free, Caroline; McCarthy, Ona L; Palmer, Melissa J; Knight, Rosemary; Edwards, Phil; French, Rebecca; Baraitser, Paula; Hickson, Ford Colin Ian; Wellings, Kaye; Roberts, Ian; Bailey, Julia V; Hart, Graham; Michie, Susan; Clayton, Tim; Ploubidis, George B; Carpenter, James R; Turner, Katy ME; Devries, Karen; Potter, Kimberley

Safetxt: a safer sex intervention delivered by mobile phone messaging on sexually transmitted infections (STI) among young people in the UK - protocol for a randomised controlled trial. Journal Article

BMJ OPEN, 10 (3), pp. e031635–, 2020.

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Mahmood, A; Needham, K; Shakur-Still, Haleema; Davies, D; Belli, A; Jamaluddin, SF; Harris, T; Mohamed, FL; Leech, C; Lotfi, H; Moss, P; Hopkins, P; Wong, D; Kendall, J; Boyle, A; Wilson, M; Darwent, M; Roberts, I

Tranexamic acid in traumatic brain injury: an explanatory study nested within the CRASH-3 trial Journal Article

European Journal of Trauma and Emergency Surgery, 2020.

Abstract | Links | BibTeX

2019

Mahmood, Abda; Roberts, Ian; Shakur-Still, Haleema

A nested randomised trial of the effect of tranexamic acid on intracranial haemorrhage and infarction in traumatic brain injury (CRASH-3 trial intracranial bleeding mechanistic study): Statistical analysis plan. Journal Article

Wellcome open research, 3 , pp. 99–, 2019.

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Tillin, Therese; Tuson, Claire; Sowa, Barbara; Chattopadhyay, Kaushik; Sattar, Naveed; Welsh, Paul; Roberts, Ian; Ebrahim, Shah; Kinra, Sanjay; Hughes, A; Chaturvedi, Nishi

Yoga and Cardiovascular Health Trial (YACHT): a UK-based randomised mechanistic study of a yoga intervention plus usual care versus usual care alone following an acute coronary event. Journal Article

BMJ open, 9 (11), pp. e030119–, 2019.

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Cornelissen, Laura; Woodd, Susannah; Shakur-Still, Haleema; Fawole, Bukola; Noor, Shehla; Etuk, Saturday; Akintan, Adesina Lawrence; Chaudhri, Rizwana; Roberts, Ian

Secondary analysis of the WOMAN trial to explore the risk of sepsis after invasive treatments for postpartum hemorrhage. Journal Article

International journal of gynaecology and obstetrics, 146 (2), pp. 231–237, 2019.

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Brenner, Amy; Afolabi, Adefemi; Ahmad, Syed Masroor; Arribas, Monica; Chaudhri, Rizwana; Coats, Timothy; Cuzick, Jack; Gilmore, Ian; Hawkey, Christopher; Jairath, Vipul; Javaid, Kiran; Kayani, Aasia; Mutti, Muttiullah; Nadeem, Muhammad Arif; Shakur-Still, Haleema; Stanworth, Simon; Veitch, Andrew; Roberts, Ian; Collaborators, HALT-IT Trial

Tranexamic acid for acute gastrointestinal bleeding (the HALT-IT trial): statistical analysis plan for an international, randomised, double-blind, placebo-controlled trial. Journal Article

Trials, 20 (1), pp. 467–, 2019.

Abstract | Links | BibTeX

Sprigg, Nikola; Flaherty, Katie; Appleton, Jason P; Salman, Rustam Al-Shahi; Bereczki, Daniel; Beridze, Maia; Ciccone, Alfonso; Collins, Ronan; Dineen, Robert A; Duley, Lelia; José, Juan; England, Timothy J; Karlinski, Michal; Krishnan, Kailash; Laska, Ann Charlotte; Law, Zhe Kang; Ovesen, Christian; Ozturk, Serefnur; Pocock, Stuart J; Roberts, Ian; Robinson, Thompson G; Roffe, Christine; Peters, Nils; Scutt, Polly; Thanabalan, Jegan; Werring, David; Whynes, David; Woodhouse, Lisa; Bath, Philip M

Tranexamic acid to improve functional status in adults with spontaneous intracerebral haemorrhage: the TICH-2 RCT. Journal Article

Health technology assessment, 23 (35), pp. 1–48, 2019.

Abstract | Links | BibTeX

Beaumont, Danielle; Arribas, Monica; Frimley, Lauren; Balogun, Eni; Roberts, Ian; Shakur-Still, Haleema

Trial management: we need a cadre of high-class triallists to deliver the answers that patients need. Journal Article

Trials, 20 (1), pp. 354–, 2019.

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Ker, Katharine; Prieto-Merino, David; Sprigg, Nikola; Mahmood, Abda; Bath, Philip; Law, Zhe Kang; Flaherty, Katie; Roberts, Ian

The effectiveness and safety of anti-fibrinolytics in patients with acute intracranial haemorrhage: statistical analysis plan for an individual patient data meta-analysis Journal Article

Wellcome Open Research, 2 , pp. 120–120, 2019.

Abstract | Links | BibTeX

Ageron, Francois-Xavier; Gayet-Ageron, Angele; Steyerberg, Ewout; Bouzat, Pierre; Roberts, Ian

Prognostic model for traumatic death due to bleeding: cross-sectional international study. Journal Article

BMJ Open, 9 (5), pp. e026823–, 2019.

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Brenner, Amy; Ker, Katharine; Shakur-Still, Haleema; Roberts, Ian

Tranexamic acid for post-partum haemorrhage: What, who and when. Journal Article

Best Practice & Research Clinical Obstetrics & Gynaecology, 61 , pp. 66–74, 2019.

Abstract | Links | BibTeX

Dallaku, Kastriot; Shakur-Still, Haleema; Beaumont, Danielle; Roberts, Ian; Huque, Sumaya; Delius, Maria; Holdenrieder, Stefan; Gliozheni, Orion; Mansmann, Ulrich

No effect of tranexamic acid on platelet function and thrombin generation (ETAPlaT) in postpartum haemorrhage: a randomised placebo-controlled trial. Journal Article

Wellcome Open Research, 4 , pp. 21–, 2019.

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Dallaku, Kastriot; Shakur-Still, Haleema; Beaumont, Danielle; Roberts, Ian; Huque, Sumaya; Delius, Maria; Holdenrieder, Stefan; Gliozheni, Orion; Mansmann, Ulrich

No effect of tranexamic acid on platelet function and thrombin generation (ETAPlaT) in postpartum haemorrhage: a randomised placebo-controlled trial. Journal Article

Wellcome open research, 4 , pp. 21–, 2019.

Abstract | Links | BibTeX

2018

Ker, Katharine; Roberts, Ian; Chaudhri, Rizwana; Fawole, Bukola; Beaumont, Danielle; Balogun, Eni; Prowse, Danielle; Pepple, Tracey; Javaid, Kiran; Kayani, Aasia; Arulkumaran, Sabaratnam; Bates, Imelda; Shakur-Still, Haleema; trial collaborators, WOMAN-2

Tranexamic acid for the prevention of postpartum bleeding in women with anaemia: study protocol for an international, randomised, double-blind, placebo-controlled trial. Journal Article

Trials, 19 (1), pp. 712–, 2018.

Abstract | Links | BibTeX

Picetti, Roberto; Shakur-Still, Haleema; Medcalf, Robert L; Standing, Joseph F; Roberts, Ian

What concentration of tranexamic acid is needed to inhibit fibrinolysis? A systematic review of pharmacodynamics studies. Journal Article

Blood coagulation & fibrinolysis, 30 (1), pp. 1–10, 2018.

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Nishijima, Daniel K; VanBuren, John; Hewes, Hilary A; Myers, Sage R; Stanley, Rachel M; Adelson, David P; Barnhard, Sarah E; Bobinski, Matthew; Ghetti, Simona; Holmes, James F; Roberts, Ian; Schalick, Walton O; Tran, Nam K; Tzimenatos, Leah S; Dean, Michael J; Kuppermann, Nathan; of the Re, TIC-TOC Collaborators Pediatric Emergency Care Applied

Traumatic injury clinical trial evaluating tranexamic acid in children (TIC-TOC): study protocol for a pilot randomized controlled trial. Journal Article

Trials, 19 (1), pp. 593–, 2018.

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Brenner, Amy; Arribas, Monica; Cuzick, Jack; Jairath, Vipul; Stanworth, Simon; Ker, Katharine; Shakur-Still, Haleema; Roberts, Ian

Outcome measures in clinical trials of treatments for acute severe haemorrhage. Journal Article

Trials, 19 (1), pp. 533–, 2018.

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Roberts, Ian; Belli, Antonio; Brenner, Amy; Chaudhri, Rizwana; Fawole, Bukola; Harris, Tim; Jooma, Rashid; Mahmood, Abda; Shokunbi, Temitayo; Shakur, Haleema

Tranexamic acid for significant traumatic brain injury (The CRASH-3 trial): Statistical analysis plan for an international, randomised, double-blind, placebo-controlled trial Journal Article

Wellcome Open Research, 3 , pp. 86–86, 2018.

Abstract | Links | BibTeX

Shakur-Still, Haleema; Roberts, Ian; Fawole, Bukola; Kuti, Modupe; Olayemi, Oladapo O; Bello, Adenike; Huque, Sumaya; Ogunbode, Olayinka; Kotila, Taiwo; Aimakhu, Chris; Okunade, Olujide A; Olutogun, Tolulase; Adetayo, Cecilia O; Dallaku, Kastriot; Mansmann, Ulrich; Hunt, Beverley J; Pepple, Tracey; Balogun, Eni

Effect of tranexamic acid on coagulation and fibrinolysis in women with postpartum haemorrhage (WOMAN-ETAC): a single-centre, randomised, double-blind, placebo-controlled trial. Journal Article

Wellcome open research, 3 , pp. 100–, 2018.

Abstract | Links | BibTeX

Shakur-Still, Haleema; Roberts, Ian; Fawole, Bukola; Kuti, Modupe; Olayemi, Oladapo; Bello, Adenike; Huque, Sumaya; Ogunbode, Olayinka; Kotila, Taiwo; Aimakhu, Chris; Okunade, Olujide; Olutogun, Tolulase; Adetayo, Cecilia; Dallaku, Kastriot; Mansmann, Ulrich; Hunt, Beverley; Pepple, Tracey; Balogun, Eni

Effect of tranexamic acid on coagulation and fibrinolysis in women with postpartum haemorrhage (WOMAN-ETAC): a single-centre, randomised, double-blind, placebo-controlled trial Journal Article

Wellcome Open Research, 3 (100), pp. 14722–, 2018.

Abstract | Links | BibTeX

Roberts, Ian; Belli, Antonio; Brenner, Amy; Chaudhri, Rizwana; Fawole, Bukola; Harris, Tim; Jooma, Rashid; Mahmood, Abda; Shokunbi, Temitayo; Shakur-Still, Haleema

Tranexamic acid for significant traumatic brain injury (The CRASH-3 trial): Statistical analysis plan for an international, randomised, double-blind, placebo-controlled trial Journal Article

Wellcome Open Research, 3 , pp. 86–86, 2018.

Abstract | Links | BibTeX

Roberts, Ian; Belli, Antonio; Brenner, Amy; Chaudhri, Rizwana; Fawole, Bukola; Harris, Tim; Jooma, Rashid; Mahmood, Abda; Shokunbi, Temitayo; Shakur-Still, Haleema; trial collaborators, CRASH-3

Tranexamic acid for significant traumatic brain injury (The CRASH-3 trial): Statistical analysis plan for an international, randomised, double-blind, placebo-controlled trial. Journal Article

Wellcome open research, 3 , pp. 86–, 2018.

Abstract | Links | BibTeX

Houghton, G; Kingdon, C; Dower, M; Shakur-Still, Haleema; Alfirevic, Z

What women think about consent to research at the time of an obstetric emergency: a qualitative study of the views of a cohort of World Maternal Antifibrinolytic Trial participants. Journal Article

BJOG, 125 (13), pp. 1744–1753, 2018.

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Houghton, G; Kingdon, C; Dower, M; Shakur-Still, Haleema; Alfirevic, Z

What women think about consent to research at the time of an obstetric emergency: a qualitative study of the views of a cohort of World Maternal Antifibrinolytic Trial participants. Journal Article

BJOG, 125 (13), pp. 1744–1753, 2018.

Abstract | Links | BibTeX

Roberts, Ian

Women's work in UK clinical trials is undervalued. Journal Article

Lancet, 392 (10149), pp. 732–, 2018.

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Brenner, Amy; Shakur-Still, Haleema; Chaudhri, Rizwana; Fawole, Bukola; Arulkumaran, Sabaratnam; Roberts, Ian; Collaborators, WOMAN Trial

The impact of early outcome events on the effect of tranexamic acid in post-partum haemorrhage: an exploratory subgroup analysis of the WOMAN trial. Journal Article

BMC pregnancy and childbirth, 18 (1), pp. 215–, 2018.

Abstract | Links | BibTeX

Huque, Sumaya; Roberts, Ian; Fawole, Bukola; Chaudhri, Rizwana; Arulkumaran, Sabaratnam; Shakur-Still, Haleema

Risk factors for peripartum hysterectomy among women with postpartum haemorrhage: analysis of data from the WOMAN trial. Journal Article

BMC pregnancy and childbirth, 18 (1), pp. 186–, 2018.

Abstract | Links | BibTeX

Roberts, Ian; Shakur-Still, Haleema; Bellomo, Rinaldo; Bion, Julian; Finfer, Simon; Hunt, Beverley; Myburgh, John; Perner, Anders; Reinhart, Konrad

Should hydroxyethyl starch be banned? - Authors' reply. Journal Article

Lancet, 392 (10142), pp. 119–, 2018.

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Sprigg, Nikola; Flaherty, Katie; Appleton, Jason P; Salman, Rustam Al-Shahi; Bereczki, Daniel; Beridze, Maia; Christensen, Hanne; Ciccone, Alfonso; Collins, Ronan; Czlonkowska, Anna; Dineen, Robert A; Duley, Lelia; Egea-Guerrero, Juan Jose; England, Timothy J; Krishnan, Kailash; Laska, Ann Charlotte; Law, Zhe Kang; Ozturk, Serefnur; Pocock, Stuart J; Roberts, Ian; Robinson, Thompson G; Roffe, Christine; Seiffge, David; Scutt, Polly; Thanabalan, Jegan; Werring, David; Whynes, David; Bath, Philip M; Investigators, TICH-2

Tranexamic acid for hyperacute primary IntraCerebral Haemorrhage (TICH-2): an international randomised, placebo-controlled, phase 3 superiority trial. Journal Article

Lancet, 391 (10135), pp. 2107–2115, 2018.

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Roberts, Ian; Shakur-Still, Haleema; Fawole, Bukola; Kuti, Modupe; Olayemi, Oladapo; Bello, Adenike; Ogunbode, Olayinka; Kotila, Taiwo; Aimakhu, Chris O; Olutogun, Tolulase; Hunt, Beverley J; Huque, Sumaya

Haematological and fibrinolytic status of Nigerian women with post-partum haemorrhage. Journal Article

BMC pregnancy and childbirth, 18 (1), pp. 143–, 2018.

Abstract | Links | BibTeX

Kiriya, Junko; Edwards, Phil; Roberts, Ian

Effect of emotional content on online video sharing among health care professionals and researchers (DIFFUSION): results and lessons learnt from a randomised controlled trial. Journal Article

BMJ open, 8 (4), pp. e019419–, 2018.

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Shakur-Still, Haleema; Beaumont, Danielle; Pavord, Sue; Gayet-Ageron, Angele; Ker, Katharine; Mousa, Hatem A

Antifibrinolytic drugs for treating primary postpartum haemorrhage. Journal Article

The Cochrane database of systematic reviews, 2 (2), pp. CD012964–, 2018.

Abstract | Links | BibTeX

Roberts, Ian; Shakur-Still, Haleema; Bellomo, Rinaldo; Bion, Julian; Finfer, Simon; Hunt, Beverley; Myburgh, John; Perner, Anders; Reinhart, Konrad

Hydroxyethyl starch solutions and patient harm. Journal Article

Lancet, 391 (10122), pp. 736–, 2018.

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Dineen, Rob A; Pszczolkowski, Stefan; Flaherty, Katie; Law, Zhe K; Morgan, Paul S; Roberts, Ian; Werring, David J; Salman, Rustam Al-Shahi; England, Tim; Bath, Philip M; Sprigg, Nikola

Does tranexamic acid lead to changes in MRI measures of brain tissue health in patients with spontaneous intracerebral haemorrhage? Protocol for a MRI substudy nested within the double-blind randomised controlled TICH-2 trial. Journal Article

BMJ open, 8 (2), pp. e019930–, 2018.

Abstract | Links | BibTeX

Hibbs, Stephen P; Roberts, Ian; Shakur-Still, Haleema; Hunt, Beverley J

Post-partum haemorrhage and tranexamic acid: a global issue. Journal Article

British journal of haematology, 180 (6), pp. 799–807, 2018.

Abstract | Links | BibTeX

Shakur-Still, Haleema; Roberts, Ian

Finding Better Ways to Prevent Postpartum Hemorrhage. Journal Article

The New England journal of medicine, 379 (8), pp. 790–792, 2018.

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2017

Ker, Katharine; Prieto-Merino, David; Sprigg, Nikola; Mahmood, Abda; Bath, Philip; Law, Zhe Kang; Flaherty, Katie; Roberts, Ian

The effectiveness and safety of anti-fibrinolytics in patients with acute intracranial haemorrhage: statistical analysis plan for an individual patient data meta-analysis. Journal Article

Wellcome open research, 2 , pp. 120–, 2017.

Abstract | Links | BibTeX

Herrett, Emily; Williamson, Elizabeth; Beaumont, Danielle; Prowse, Danielle; Youssouf, Nabila; Brack, Kieran; Armitage, Jane; Goldacre, Ben; MacDonald, Thomas; van Staa, Tjeerd; Roberts, Ian; Shakur-Still, Haleema; Smeeth, Liam

Study protocol for statin web-based investigation of side effects (StatinWISE): a series of randomised controlled N-of-1 trials comparing atorvastatin and placebo in UK primary care. Journal Article

BMJ open, 7 (12), pp. e016604–, 2017.

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Li, Bernadette; Miners, Alec; Shakur-Still, Haleema; Roberts, Ian; Collaborators, WOMAN Trial

Tranexamic acid for treatment of women with post-partum haemorrhage in Nigeria and Pakistan: a cost-effectiveness analysis of data from the WOMAN trial. Journal Article

The Lancet Global health, 6 (2), pp. e222–e228, 2017.

Abstract | Links | BibTeX

Gayet-Ageron, Angèle; Prieto-Merino, David; Ker, Katharine; Shakur-Still, Haleema; Ageron, François-Xavier; Roberts, Ian; Collaboration, Antifibrinolytic Trials

Effect of treatment delay on the effectiveness and safety of antifibrinolytics in acute severe haemorrhage: a meta-analysis of individual patient-level data from 40 138 bleeding patients. Journal Article

Lancet, 391 (10116), pp. 125–132, 2017.

Abstract | Links | BibTeX

Roberts, Ian; Shakur-Still, Haleema

Tranexamic acid for post-partum haemorrhage in the WOMAN trial - Authors' reply. Journal Article

Lancet, 390 (10102), pp. 1584–, 2017.

Links | BibTeX

Mahmood, Abda; Roberts, Ian; Shakur-Still, Haleema

A nested mechanistic sub-study into the effect of tranexamic acid versus placebo on intracranial haemorrhage and cerebral ischaemia in isolated traumatic brain injury: study protocol for a randomised controlled trial (CRASH-3 Trial Intracranial Bleeding Mechanistic Sub-Study [CRASH-3 IBMS]). Journal Article

Trials, 18 (1), pp. 330–, 2017.

Abstract | Links | BibTeX

Reith, Florence CM; Lingsma, Hester F; Gabbe, Belinda J; Lecky, Fiona E; Roberts, Ian; Maas, Andrew IR

Differential effects of the Glasgow Coma Scale Score and its Components: An analysis of 54,069 patients with traumatic brain injury. Journal Article

Injury, 48 (9), pp. 1932–1943, 2017.

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Roberts, Ian; Edwards, Phil; Prieto, David; Joshi, Miland; Mahmood, Abda; Ker, Katharine; Shakur-Still, Haleema

Tranexamic acid in bleeding trauma patients: an exploration of benefits and harms. Journal Article

Trials, 18 (1), pp. 48–, 2017.

Abstract | Links | BibTeX

2016

McCarthy, Ona L; French, Rebecca S; Baraitser, Paula; Roberts, Ian; Rathod, Sujit D; Devries, Karen; Bailey, Julia V; Edwards, Phil; Wellings, Kaye; Michie, Susan; Free, Caroline

Safetxt: a pilot randomised controlled trial of an intervention delivered by mobile phone to increase safer sex behaviours in young people. Journal Article

BMJ open, 6 (12), pp. e013045–, 2016.

Abstract | Links | BibTeX

Shakur-Still, Haleema; Fawole, Bukola; Kuti, Modupe; Olayemi, Oladapo; Bello, Adenike; Ogunbode, Olayinka; Kotila, Taiwo; Aimakhu, Chris O; Huque, Sumaya; Gregg, Meghann; Roberts, Ian

Effect of tranexamic acid on coagulation and fibrinolysis in women with postpartum haemorrhage (WOMAN-ETAC): protocol and statistical analysis plan for a randomized controlled trial. Journal Article

Wellcome open research, 1 , pp. 31–, 2016.

Abstract | Links | BibTeX

Dallaku, Kastriot; Shakur-Still, Haleema; Edwards, Phil; Beaumont, Danielle; Roberts, Ian; Huque, Sumaya; Delius, Maria; Mansmann, Ulrich

Statistical analysis plan for the WOMAN-ETAPlaT study: Effect of tranexamic acid on platelet function and thrombin generation. Journal Article

Wellcome open research, 1 , pp. 30–, 2016.

Abstract | Links | BibTeX

Dallaku, Kastriot; Shakur-Still, Haleema; Roberts, Ian; Edwards, Phil; Beaumont, Danielle; Delius, Maria; Siegmund, Braun; Gliozheni, Orion; Tasha, Ilir; Cenameri, Saimir; Mansmann, Ulrich

Effects of tranexamic acid on platelet function and thrombin generation (ETAPlaT): WOMAN trial sub-study. Journal Article

Scientific reports, 1 , pp. 29–, 2016.

Abstract | Links | BibTeX

151 entries « 1 of 4 »