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Completed Trial
Completed Trial
WOMAN Trial

Around the world, one woman dies every five minutes from excessive bleeding after giving birth, a medical complication known as postpartum haemorrhage. The majority of these women live in low- and middle-income countries where access to life-saving emergency healthcare is often limited.  The...

Current Trial
Current Trial
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Trauma-INTACT

Trauma-INTACT is a prospective, open-label, multicentre, pharmacokinetic study. Objective:  To assess the population pharmacokinetics of intramuscular TXA in trauma patients. Background:  The anti-fibrinolytic TXA has been licensed for over 30 years for use in the prevention and...

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Current Trial
Current Trial
WOMAN-2

Postpartum haemorrhage (PPH) is responsible for about 100,000 maternal deaths every year, almost all of which occur in low and middle income countries. When given within three hours of birth, tranexamic acid reduces deaths due to bleeding in women with PPH by almost one third. However, for many...

Completed Trial
Completed Trial
CRASH-2

The CRASH-2 trial: a randomised controlled trial and economic evaluation of the effects of tranexamic acid on death, vascular occlusive events and transfusion requirement in bleeding trauma patients. Among trauma patients who survive to reach hospital, exsanguination is a common cause of...

Current Trial
Current Trial
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StatinWISE

StatinWISE is a trial designed to find out whether the muscle symptoms experienced during statin use are caused by statins.  

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Current Trial
Current Trial
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ARREST

A randomised trial of expedited transfer to a cardiac arrest centre for non-ST elevation out-of-hospital cardiac arrest. The aim is to determine the best post-resuscitation care pathway for patients without ST-segment elevation (STE). We propose that changes to emergency management comprising...

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Current Trial
HALT-IT

The HALT-IT trial is a a large, international trial assessing whether early administration of tranexamic acid in people with acute gastrointestinal bleeding can reduce their risk of dying in the hospital.  

Current Trial
Current Trial
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ERIC-PPCI

Effect of Remote Ischaemic Conditioning on clinical outcomes in ST-segment elevation myocardial infarction patients undergoing Primary Percutaneous Coronary Intervention : A multicentre randomised controlled clinical trial. The aim of this trial is to determine whether remote ischaemic...

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Current Trial
Current Trial
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PREVENTT

A randomised double-blind controlled phase III study to compare the efficacy and safety of intravenous ferric carboxymaltose with placebo in patients with anaemia undergoing major open abdominal surgery. The aim of this trial is to determine if a single dose of intravenous iron administered to...

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Current Trial
Current Trial
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REVIVED BCIS 2

Revascularisation for Ischaemic Ventricular Dysfunction. The aim of this trial is to evaluate the efficacy and safety of percutaneous coronary intervention compared to optimal medical therapy alone for ischaemic left ventricular dysfunction. http://revived.lshtm.ac.uk/

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