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Postpartum haemorrhage (PPH) is responsible for about 100,000 maternal deaths every year, almost all of which occur in low and middle income countries. When given within three hours of birth, tranexamic acid reduces deaths due to bleeding in women with PPH by almost one third. However, for many women, treatment of PPH is too late to prevent death and severe morbidities. Over one-third of pregnant women in the world are anaemic and many are severely anaemic. We are doing the WOMAN-2 trial to see if giving tranexamic acid can prevent PPH and other severe outcomes in women with moderate and severe anaemia.

WOMAN-2 is planned to take place in Africa and in Asia.


Trial set-up


20 March 2018


31 January 2023


Key contacts

Shakur-Still, Haleema

Professor of Global Health Clinical Trials


Haleema Shakur-Still is a Professor of Global Health Clinical Trials and Co-Director of the Clinical Trials Unit (CTU) at the London School of Hygiene and Tropical Medicine (LSHTM). Haleema has worked over 16 years in global health clinical trials with a specific focus on emergency care. Her...