WOMAN Trial Results and News

WOMAN Trial Results and News

Can we prevent women from dying after childbirth?

Every year 14 million mothers develop severe bleeding after childbirth or postpartum haemorrhage (PPH) as it is also known, and about 2% of them will die, with an average of 2-4 hours from the start of bleeding to death.

The WOMAN trial aims to provide research-based information, as to whether an old drug, Tranexamic Acid (TXA), can improve the outcomes for women who develop this life-threatening condition and ultimately save lives.

The WOMAN trial showed that if given within 3 hours, TXA can reduce the risk of death due to bleeding by one third.


The WOMAN Trial investigated the effect of early tranexamic acid administration on mortality, hysterectomy, and other morbidities in women with post-partum haemorrhage (WOMAN) and was an international, randomised, double-blind, placebo-controlled trial.

Over 200 million women become pregnant each year. Despite great progress during the past three decades, deaths during pregnancy and childbirth remain a serious (and largely preventable) risk for women in around 75 countries where 98% of maternal mortality occurs.

The WOMAN Trial tested TXA for the treatment of postpartum haemorrhage patients. The trial tested whether tranexamic acid, a blood clot stabiliser that was discovered in Japan in the 1950s, could become an essential tool for fighting excessive bleeding soon after giving birth. This condition, known as postpartum haemorrhage, is the number one cause of maternal death around the world, particularly in low and middle-income countries.

The WOMAN trial showed that if given within 3 hours, TXA can reduce the risk of death due to bleeding by one third.

The trial also shows that tranexamic acid reduces the need for surgery to control bleeding (laparotomy) by more than a third. There were no side effects observed from the drug for either mothers or babies.

Read The WOMAN Trial published by The Lancet HERE

Visit the WOMAN Trial website for more trial news:

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